

A few facts about Baclofen (Lioresal) medication in general:
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Baclofen (Lioresal) Side Effects - The most common is transient drowsiness (10–63%). In one controlled study of 175 patients, transient drowsiness was observed in 63% of those receiving Baclofen (Lioresal Intrathecal) compared to 36% of those in the placebo group. Other common adverse reactions are dizziness (5–15%), weakness (5–15%) and fatigue (2–4%).
Baclofen (Lioresal Intrathecal) Respiratory side effects including apnea, dyspnea, and hyperventilation have been reported. Cases of acute bronchospasm (particularly in patients with asthma) have been reported rarely. Baclofen (Lioresal Intrathecal) Cardiovascular side effects including hypertension, bradycardia, and orthostatic hypotension have been reported.
Usual Adult dosage of Baclofen (Gablofen) for Muscle Spasm: Oral: Initial dose: 5 mg orally 3 times a day for 3 days, then 10 mg orally 3 times a day for 3 days, then 15 mg orally 3 times a day for 3 days, then 20 mg orally 3 times a day. Maintenance dose: 40-80 mg/day. 80 mg/day dosages should be administered in 4 divided doses.
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Baclofen (Gablofen) for Migraine Prevention: I have had migraines for 6 years and have tried every medication from, Topamax to Zonegran to Depakote. Since I've started taking Baclofen (Intrathecal) 20mg x 3 times daily, 6 months ago, I have had one breakthrough headache and even then I was able to function. I'm not saying Baclofen is the "perfect migraine prevention medicine" but for me, it's been my miracle pill.
Baclofen for Muscle Spasm: I have been suffering from a dull and persistent pain on the right side of my abdomen near my rib cage for several months. I had blood tests and abdominal ultrasound with results indicating "normal" appearance. The pain persisted and I could control it to some extent (not great) with Tylenol extra strength. Then I asked my doctor to prescribe 10mg Baclofen, which I have been taking 3 times daily for about two weeks. I noticed my abdominal pain eased after 2 days of the medication. I haven't been experiencing abdominal pain except on rare occasion since I have been taking Baclofen (Gablofen). I feel totally functional and thankful that I don't have to live in pain any longer.
Baclofen (Intrathecal) for Muscle Spasm: I have suffered with back pain and muscle spasms for almost ten years. Sleeping through the night only happened in my dreams. Travel was limited by the necessity to stop frequently, get out and walk/stretch. A 200 mile trip could take 6 hours. Hotel beds were excruciating. After three weeks of routine dosing, my dreams are now a reality. Sleeping thru the night, driving for extended periods and staying away from home overnight have given me my life back.
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And here we have more facts about Baclofen (Gablofen) medication should be mentioned:
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Baclofen (Gablofen) Gastrointestinal side effects including nausea, vomiting, constipation, abdominal pain, diarrhea, dysphagia, fecal incontinence, gastrointestinal hemorrhage, and tongue disorder have been reported (especially with rapid dose increases).
Baclofen (Gablofen) General side effects have included effects on sleep. One study has reported that a single, therapeutic dose of Baclofen (Lioresal Intrathecal) alters sleep architecture and produces a small reduction in mean sleep oxygen saturation, but does not significantly increase sleep disordered breathing.
Baclofen (Gablofen) may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Drinking alcohol can increase certain side effects of Baclofen. Do not use Baclofen (Lioresal) at a time when muscle tone is needed to assure safe balance and movement for certain activities. In some situations, it may endanger your physical safety to be in a state of reduced muscle tone.
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And of course some more opinions about Baclofen (Lioresal Intrathecal) pills from some patients:
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Baclofen (Intrathecal) for Muscle Spasm: I have severe muscle spasms due to Multiple Sclerosis. I don't know where I would be without this medication. I will most likely have to go up a notch on my dosage very soon but it helps greatly so I don't care as long as it keeps helping me.
Baclofen (Lioresal) for Muscle Spasm: With 20 years of MS under my belt, it keeps me moving.
Baclofen (Lioresal) for Muscle Spasm: its good medication due to its rapid onset of action , safety on GIT tract ,relief of pain begins after few hours of absorption
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