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Baclofen (Gablofen) Genitourinary side effects including urinary frequency have been reported in 2% to 6% of treated patients. Enuresis, urinary retention, dysuria, abnormal ejaculation, kidney calculus, oliguria, vaginitis and impotence have also been reported.

Baclofen (Lioresal Intrathecal) Respiratory side effects including apnea, dyspnea, and hyperventilation have been reported. Cases of acute bronchospasm (particularly in patients with asthma) have been reported rarely. Baclofen (Lioresal Intrathecal) Cardiovascular side effects including hypertension, bradycardia, and orthostatic hypotension have been reported.

Usual Adult dose of Baclofen (Lioresal Intrathecal) for Muscle Spasm: Oral: Initial dose: 5 mg orally 3 times a day for 3 days, then 10 mg orally 3 times a day for 3 days, then 15 mg orally 3 times a day for 3 days, then 20 mg orally 3 times a day. Maintenance dosage: 40-80 mg/day. 80 mg/day doses should be administered in 4 divided doses.

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Baclofen (Lioresal) for Muscle Spasm: After trying several muscle relaxers with no improvement, my new pain management health care professional put me on 10mg Baclofen (Intrathecal) 3 x daily.I was extremely drowsy the first week, by second week had complete resolution of my lower back pain following 2 lumbar surgeries to correct scoliosis. First time I can walk and stand straight up in years. Initially helped my neck pain, but is now no longer effective. Having surgery tomorrow to repair subluxation of C3/4, hoping that resolves my pain. Status post surgery x 5 for cervical herniations. May need to adjust dose? Great medicine, highly recommended.

Baclofen (Lioresal) for Migraine Prevention: I have had migraines for 6 years and have tried every medication from, Topamax to Zonegran to Depakote. Since I've started taking Baclofen 20mg x 3 times daily, 6 months ago, I have had one breakthrough headache and even then I was able to function. I'm not saying Baclofen (Lioresal) is the "perfect migraine prevention medicine" but for me, it's been my miracle pill.

Baclofen (Gablofen) for Spasticity: This drug works. If I am late with a dose or miss a dose I feel it. I can't go through the day without it.

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Buddha: Health is the greatest gift, contentment the greatest wealth, faithfulness the best relationship.

Mignon McLaughlin: If the pain wanders, do not waste your time with doctors.

William Falconer: Mental agitations and eating cares are more injurious to health, and destructive of life, than is commonly imagined, and could their effects be collected, would make no inconsiderable figure in the bills of mortality.

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Baclofen (Lioresal) is a muscle relaxer and an antispastic agent. Baclofen (Lioresal Intrathecal) is used to treat muscle symptoms caused by multiple sclerosis, including spasm, pain, and stiffness. Baclofen may also be used for purposes not listed in this medication guide.

If you miss a dose of Baclofen, use it as soon as possible. If it is almost time for your next dose, skip the missed dosage and go back to your regular dosing schedule. Do not use 2 doses at once.

FDA pregnancy category C. It is not known whether Baclofen (Lioresal) will harm an unborn baby. Tell your healthcare professional if you are pregnant or plan to become pregnant while using this medication. It is not known whether Baclofen (Gablofen) passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using Baclofen (Lioresal Intrathecal). Do not give this medication to a child younger than 12 years old. Older adults may be more sensitive to the effects of this medicine.

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And of course some more opinions about Baclofen (Lioresal) drug from different patients:

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I Was diagnosed with a herniated L4 three years ago and had just recently had a flare up of spasms in my lower and mid back. In the past the health care professional has prescribed Flexoril and Robaxin for my muscle pain/spasms and it worked poorly. Now that i have been prescribed Baclofen (Lioresal), i have had great results. Have had the best sleep in months due to the help with this drug.

Baclofen (Intrathecal) for Muscle Spasm: With 20 years of MS under my belt, it keeps me moving.

Baclofen (Lioresal) for Cervical Dystonia: I take 10mg 3 x daily for cervical dystonia and it has helped me a lot. I also go for regular botox injections in my neck and the Baclofen (Lioresal) takes the edge away and makes it bearable on an everyday basis. No apparent side effects although I have become forgetful.

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