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Baclofen (Lioresal Intrathecal) Side Effects - The most common is transient drowsiness (10–63%). In one controlled study of 175 patients, transient drowsiness was observed in 63% of those receiving Baclofen (Lioresal) compared to 36% of those in the placebo group. Other common adverse reactions are dizziness (5–15%), weakness (5–15%) and fatigue (2–4%).
Baclofen (Lioresal Intrathecal) Respiratory side effects including apnea, dyspnea, and hyperventilation have been reported. Cases of acute bronchospasm (particularly in patients with asthma) have been reported rarely. Baclofen (Lioresal Intrathecal) Cardiovascular side effects including hypertension, bradycardia, and orthostatic hypotension have been reported.
Baclofen (Lioresal) has been assigned to pregnancy category C by the FDA. Animal studies have revealed an increased incidence of omphaloceles. There are no controlled data in human pregnancy. Baclofen (Lioresal) should only be given during pregnancy when benefit outweighs risk.
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Baclofen (Lioresal) for Cervical Dystonia: I take 10mg 3 x daily for cervical dystonia and it has helped me a lot. I also go for regular botox injections in my neck and the Baclofen (Lioresal) takes the edge away and makes it bearable on an everyday basis. No apparent side effects although I have become forgetful.
Baclofen (Lioresal) for Muscle Spasm: This medicine saved me during a sudden, incredibly intense muscle spasm in my neck/back. Side effects were mostly drowsiness but it gave me time to heal and let me sleep during the painful period. Great medication.
Baclofen for Hiccups: We tried it for my dad when he was having non-stop hiccups for weeks after having TIA. It definitely worked when he used the medication. It's a lot of help indeed.
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Also if you're not sick of reading - here are a few interesting words about healthy life from some well-known persons:
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Robert Burton: Diseases crucify the soul of man, attenuate our bodies, dry them, wither them, rivel them up like old apples, make them as so many Anatomies.
Lucius Annaeus Seneca: We can be thankful to a friend for a few acres, or a little money; and yet for the freedom and command of the whole earth, and for the great benefits of our being, our life, health, and reason, we look upon ourselves as under no obligation.
Robert Orben: Quit worrying about your health. It'll go away.
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And here we have more facts about Baclofen (Lioresal) medication should be said:
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Seek medical attention right away if any of these severe side effects occur: severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision; confusion; frequent urination; increased weakness of arms or legs; seizures; slurred speech; sore throat; vomiting.
Baclofen Side Effects Cardiovascular: Hypotension (0–9%). Rare instances of dyspnea, palpitation, chest pain, syncope. Baclofen (Lioresal Intrathecal) Side Effects Genitourinary: Urinary frequency (2–6%); and, rarely, enuresis, urinary retention, dysuria, impotence, inability to ejaculate, nocturia, hematuria.
Baclofen Side Effects Neuropsychiatric: Confusion (1–11%), headache (4–8%), insomnia (2–7%); and, rarely, euphoria, excitement, depression, hallucinations, paresthesia, muscle pain, tinnitus, slurred speech, coordination disorder, tremor, rigidity, dystonia, ataxia, blurred vision, nystagmus, strabismus, miosis, mydriasis, diplopia, dysarthria, epileptic seizure.
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Baclofen (Gablofen) for Migraine Prevention: I have had migraines for 6 years and have tried every medication from, Topamax to Zonegran to Depakote. Since I've started taking Baclofen (Gablofen) 20mg x 3 times daily, 6 months ago, I have had one breakthrough headache and even then I was able to function. I'm not saying Baclofen (Intrathecal) is the "perfect migraine prevention medicine" but for me, it's been my miracle pill.
Baclofen (Lioresal) for Muscle Spasm: I have severe muscle spasms due to Multiple Sclerosis. I don't know where I would be without this medication. I will most likely have to go up a notch on my dosage very soon but it helps greatly so I don't care as long as it keeps helping me.
Baclofen (Lioresal) for Muscle Spasm: Take 3x/day for fibromyalgia - lifesaver! Tried almost all other muscle relaxers, and Baclofen (Intrathecal) works the best for chronic muscle spasms and pain.
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